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Function Defect Phenotype Approximate frequency Hormonal regulation KALIG 1 Prokineticin- 2 FGFR1 Kallmann syndrome, isolated gonadotropin GnRH receptor deficiency 1 10, 000 DAX 1 Adrenal hypoplasia congenita rare Steroidogenic enzymes Congenital adrenal hyperplasia rare Haemochromatosis iron deposition in gonadotroph 1 1000 FSHОІ T allele of rs10835638 oligospermia rare FSH receptor oligospermia rare Androgen receptor CAG CGG polymorphism oligospermia 1 20, 000 asthenozoospermia paxil or priligy 2014; 6 671 80
